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Functional Genomics: Analyzing Gene Expression Data

We have integrated Diamond with the Genes@Work system for analyzing gene expression data that has been developed at IBM Research's Computational Biology Center to analyze gene expression data derived from DNA microchips. A DNA microchip is a glass slide containing genetic material from a single biological cell. From DNA microchips we can obtain a set of data (usually represented as a 2D array) where each data value is a measurement of the "expression level" of a single gene in that cell. Such datasets can be used to compare the relative expression level of genes between sample and control populations of cells. The figures below show a screenshot from Genes@Work of microchip data, and visualizations produced by Diamond in analysing these data to discriminate between normal and cancerous cells.

"Gene Expression Image"
"3D scatterplot of gene expression data" "Parallel coordinates view of gene expression data"