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| Functional Genomics: Analyzing Gene Expression Data | |||||
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We have integrated Diamond with the Genes@Work system for analyzing gene expression data that has been developed at IBM Research's Computational Biology Center to analyze gene expression data derived from DNA microchips. A DNA microchip is a glass slide containing genetic material from a single biological cell. From DNA microchips we can obtain a set of data (usually represented as a 2D array) where each data value is a measurement of the "expression level" of a single gene in that cell. Such datasets can be used to compare the relative expression level of genes between sample and control populations of cells. The figures below show a screenshot from Genes@Work of microchip data, and visualizations produced by Diamond in analysing these data to discriminate between normal and cancerous cells. |
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