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Computational biology


Overview

Using computers in biomedical area becomes more and more important, because data desired to be processed become larger and larger these days. Thus we focus on designing fast algorithms and efficient data structures for problems in this area.

Research items

  • Research on cancer genes: gene finding, primer design, etc.
  • Research on HIVs: analysis of recombination in HIV, etc.
  • Research on computational theory: combinatorial pattern matching
Publications
  • Tetsuo Shibuya, Constructing the Suffix Tree of a Tree with a Large Alphabet, Proceedings of the 10th Annual International Symposium on Algorithms and Computation (ISAAC'99), Chennai, India, December 16-18, 1999, to appear.
  • Tetsuya Ueda, Hiroki Sasaki, Yoshitaka Kuwahara, Masahiko Nezu, Tetsuo Shibuya, Hiromi Sakamoto, Kazuyoshi Yanagihara, Kennichi Mafune, Masatoshi Makuuchi, and Masaaki Terada, Interstitional Deletion of the Prescribed 3' Exons of K-sam/FGFR2 Generates Preferential Expression of mRNAs Encoding Proteins Lacking a Putative Phospholipase C-gamma 1 Association Site, Cancer Research, 1999, to appear.
  • T. Shibuya and H. Imai, New Flexible Approaches for Multiple Sequence Alignment, Journal of Computational Biology, Vol. 4, No. 3, 1997, Mary Ann Liebert, Inc., pp. 385-413.
  • T. Shibuya and H. Imai, New Flexible Approaches for Multiple Sequence Alignment, Proceedings of 1st Annual International Conference on Computational Molecular Biology (RECOMB '97), Santa Fe, January 1997, pp. 267-276. (its full paper appears in J. Comput. Biol. Vol. 4, No. 3.)
  • T. Shibuya and H. Imai, Enumerating Suboptimal Alignments of Multiple Biological Sequences Efficiently, Proceedings of the Pacific Symposium on Biocomputing '97, Hawaii, January 1997, pp. 409-420.
  • T. Shibuya and H. Imai, Parametric Alignment of Multiple Biological Sequences, Proceedings of Genome Informatics 1996, Tokyo, December 1996, pp. 41-50.


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Last modified 30 October 1999