Photo
Barry Robson

Publications

1. "Biochemical Effects of the Hypoglycaemic Compound Pent-4-enoic Acid and Related Non-hypoglycaemic Fatty Acid", A. E. Senior, B. Robson and H. S. A. Sherratt, Biochem. J. (1968) 110, 511-519.
2.”Analysis of the Code Relating Sequence to Conformation in Globular Proteins", R. H. Pain and B. Robson, Nature (1970), 227, 62-63.
3."Analysis of the Code Relating Sequence to Conformation in Globular Proteins: Possible Implications for the Mechanism of Formation of Helical Regions", B. Robson and R. H. Pain, J. Mol. Biol. (1971) 58, 237-256.
4. “The Role of Sidechains in determining the Conformation of Globular Proteins", R. H. Pain and B. Robson, Proc. lst Biophys. Congress (1971) 1, 33-37.
5. "Theoretical and Experimental Studies on Protein Folding", B. Robson (1971) Ph.D. Thesis, University of Newcastle Upon Tyne
6. "Theoretical Aspects of Protein Folding: Amino acids, Peptides and Proteins", Ed. R. C. Sheppard. (1971) (The Stonebridge Press - John Wright and Sons Ltd., for: The Chemical Society)
7. Ibid. (1972)
8. Ibid (1973)
9."Directional Information Transfer in Protein Helices", B. Robson and R.H. Pain, Nature New Biology (1972) 238, 107-108.
10."Studies on the Role of the a-helix in Nucleation", B. Robson and R.H. Pain, (1972) Jerusalem Symposia on Quantum Chemistry and Biochemistry 5, Circulated Report and UNCC Newsletter
11."Conformation of Biological Molecules and Polymers", B. Robson and R.H. Pain (1973), Academic Press, Ed. B. Pullman, 161-172.
12. "Predicting How Proteins Fold Up", B. Robson Nature (1974), 248, 636.
13. "Protein Folding Made Simple", B. Robson Nature (1974), 249, 409.
14. "Missing Link in the Folding of Trypsin Inhibitor", B. Robson, Nature, (1974), 250, 707.
15."Protein Folding Experiments. Do Proteins Cheat?", B. Robson, Nature (1974), 262, 447.
16."Theoretical Aspects of Protein Folding", B. Robson, Amino Acids, Peptides and Proteins 5, (1974) 180-187.
17."Analysis of the Code Relating Sequence to Conformation in Globular Proteins: Theory and Application of Expected Information", B. Robson, Biochem. J. (1974) 141, 853-867.
18."Analysis of the Code Relating Sequence to Conformation in Globular Proteins: Development of a Stereochemical alphabet on the basis of Intra-Residue Information", B. Robson and R.H. Pain, Biochem. J. (1974) 141, 869-882.
19."Analysis of the Code Relating Sequence to Conformation in Globular Proteins: The Role of the Residue in Determining the Conformation of its Neighbours", B. Robson and R.H. Pain, Biochem. J. (1974) 141, 883-897.
20."Analysis of the Code Relating Sequence to Conformation in Globular Proteins: The Distribution of Residue Pairs and in Turns and Kinks in the Protein Chain", B. Robson and R.H. Pain, Biochem. J. (1974) 141, 899-905.
21."Comparison of Predicted and Experimentally Determined Secondary Structure of Adenylate Kinase", G. E. Schulz, C. D. Barry, J. Griedman, P. Y. Chou, G. D. Fasman, A. W. Finkelstein, V. I. Lim, O. B. Ptitsyn, E. A. Kabat, T. Wu, M. Levitt, B. Robson, K. Nagano, Nature (1974), 250, 140-142.
22."Folding Protein Along the Dotted Line", Nature (1975), 254, 386.
23."Protein Folding Path-finders", Nature (1975), 256, 89.
24."The Biochemical Grand Tour", Nature (1975), 252, 145.
25."Theoretical Aspects of Protein Folding", A. T. Hagler and B. Robson (1975) Amino acids, Peptides and Proteins 6, 206-214 with A. T. Hagler.
26."Intramolecular Interactions: from diatomics to polymers", B. Robson (1976), FEBS Letters 91, 383.
27."Protein Folding", Trends, Biochem, Sci (1976), 3, 49-51. Literature Surveys with Critical Reviews
28."Theoretical Aspects of Protein Folding", B. Robson and D. J. Osguthorpe (1976) Amino Acids Peptides and Proteins 7, (1976) 176-182
29. "Conformation Properties of Amino Acid Residues in Globular Proteins", B. Robson and E. Suzuki, J. Mol. Biol. (1976) 107, 327-356.
30. "Relationship between Helix-Coil Transition Parameters for Synthetic Polypeptides and Helix Conformation Parameters for Globular Proteins: A Simple Model", E. Suzuki and B. Robson (1976) J. Mol. Biol. 107, 357-367.
31."The Mechanism of Folding of Globular Proteins: Suitability of Penicillinase from Staphylococcus Aureus as a model for Refolding Studies", B. Robson and R.H. Pain, Biochem. J. (1976) 155, 325-330.
32."The Mechanism of Folding of Globular Proteins: Equilibria and Kinetics of Conformational Transitions of Penicillinase from Staphylococcus Aureus involving a state of Intermediate Conformation", B. Robson and R.H. Pain, Biochem. J. (1976) 155, 331-344.
33."Biological Molecules. Outmoding the Rigid View", Nature, (1977), 267, 577-578.
34."Theoretical Aspects of Protein Folding", (Ibid) 8, (1977) 181-188 B. Robson, M. Asher and D. J. Osguthorpe.
35."Conformational Energy Surfaces", B. Robson, Nature (1978) Book Review 439.
36."The Age of Aquarius?", B. Robson and M. N. Jones (1978), Nature, 272, 206.
37."Theoretical Aspects of Protein Folding", Amino Acids, B. Robson and D. J. Osguthorpe (1978) Peptides and Proteins, 9, 196-206 B.
38."Analysis of the Accuracy and Implications of Simple Methods for Predicting the Secondary Structure of Globular Proteins", J. Garnier, D. J. Osguthorpe and B. Robson (1978) J. Mol. Biol. 120, 97-120.
39."Protein Folding and Heterogeneity inside Globular Proteins", J. Crampin, B. H. Nicholson and B. Robson, Nature (1978) 272, 558-560.
40."Ab initio SCF-MO Calculations on the Architectural Unit of Peptides and Proteins", B. Robson, I. H. Hillier and M. Guest, J. Chem. Soc. (Far. Trans. II) (1978) 74, 1311-1318.
41."Conformational Behaviour of the Architectural Units of Peptides and Proteins. Assessment of Current Understanding by Ab initio Quantum Mechanical Methods and Refinement of the Dipeptide Energy Surface", I. H. Hillier and B. Robson, J. Theor. Biol. (1978) 76, 83-97.
42."The RATMOL project: Exact and approximate methods for conformational analysis of peptides and proteins", B. Robson in "Structure et Conformation des Proteines et des Peptides", CRMC2 Reports, Marseille, pp. 44-45 (1978), A Circulated Report.
43."Conformational Analysis of Peptides and Proteins", B. Robson, P. Stern, I. H. Hillier, D. J. Osguthorpe and A. T. Hagler, J. Chim. Phys. (1979) 76, 831-833.
44."Theoretical Aspects of Protein Folding", (Ibid) 10, (1979) 208-214 with D. J. Osguthorpe.
45."Classes of Protein Folding and Accuracy of Prediction", J. Garnier and B. Robson (1979), Rap. d'Activite Scientific du CECAM 1979, 147-149.
46."Refined Models for Computer Simulation of Protein Folding. Applications to the Study of Conserved Secondary Structure and Flexible Hinge Points during the Folding of Pancreatic Trypsin Inhibitor", B. Robson and D. J. Osguthorpe, J. Mol. Biol. (1979) 132, 19-51.
47."Protein Folding", B. Robson (1979), Rap. d'Activite Scientifique du CECAM 1979, 117-120.
48."Protein Folding", FEBS Letters (1980), 120, 295.
49."Monte Carlo Simulation of Water Behaviour around the Dipeptide N-Acetylalanyl-N'Methylamide", A. T. Hagler, D. J. Osguthorpe and B. Robson, Science (1980), 208, 599-601.
50."Structural Properties of Signal Peptides and their Membrane Insertion", J. Garnier, P. Gaye, J. C. Mercier and B. Robson, Biochimie (1980), 62, 231-239.
51. "Ribonuclease Still Under Attack", Nature (1980), 283, 622.
52."Designing Biologically Active Peptides", B. Robson (1980), Trends, Biochem. Sci. 2, 240-244.
53."A Comparison of the X-ray Crystallographic, NMR, and Energy Minimised Conformations of the Chemotactic peptide F-Met.Leu.Phe", P Finn, A Morffew, B. Robson, J. A. Glasel, R. J. Freer, A. R. Day. Daresbury Meeting on Simulation of Biomolecules (1981). A circulated report.
54."Ab initio Refinement of an Orbital-Centred Force Field for Biomolecules. Orbital Localisation and Parameterisation of the C-O-P(02)-O-C Fragment of Nucleotides", E. Platt, B. Robson and I. H. Hillier, (1981), J. Theor. Biol. 88, 333-353.
55."Correct Effect of Enzyme Concentration on the Michaelis-Menten Equation", B. Robson (1981) Trends Biochem. Sci. 6, XIII.
56."New Advances of Computer Simulation in Statistical Mechanics", B. Robson, Stat. Mech. and Thermodynam. Group and SERC/Collaborative Computer projects (1981) 5, 36-37.
57."Some Views of Solvation Effects in the Light of a Monte Carlo Simulation", B. Robson (1982) in "The Biophysics of Water", J, Ed. F. Franks and F. S. Mathias. John Wiley & Sons Ltd, pp. 66-70.
58."Ab initio Refinement of an Orbital-Centred Force Field for Biomolecules. 2. Applications to Peptides, Sulphonamide, and Modelling of Nucleic Acid Helices, E. Platt and B. Robson (1982) J. Theor. Biol. 96, 381-399.
59. 'Comparative Studies of Some Different Models of the Solvent Effect on the Conformation of Biological Molecules", B. Robson, G. M. Douglas, A. Metcalf, K. Woolley and J. S. Thompson (1982). 'Biophysics of Water", Ed. Felix Franks and S F Mathias. John Wiley & Sons Ltd, 21-23.
60. "Prediction of Molecular Conformation", B. Robson (1982) Biochem. Soc. Trans. 10, 297-298.
61. "A New Algorithm for Rapid Calculation of Conformational Energies", B. Robson, G. M. Douglas and E. Platt (1982) ibid, Biochem. Soc. Trans. 10, 388-389.
62."A Comment on the Thrown String Problem", B. Robson, (1982) J. Royal. Statistical Soc. (B) 44, 136-137.
63."The Calculation of Interatomic Forces", British Biophys. Soc. Abstracts "Energetics of Intermolecular Associations in Biology", B. Robson, Leeds University, page 1 (1982). A Circulated Report.
64."Theoretical Analysis of the Kinetics of Enzyme-Catalysed Reactions at High Enzyme Concentration", B. Robson and P. Millard. (1982) Circulated document. Biochem. Soc. Symposium, Oxford.
65."Predicted three-dimensional Structure of Neurotensin: Pharmacological Implications", P. W. Finn, B. Robson, E. C. Griffiths (1983), Regulatory Peptides, 7, 286.
66."Calculation of Biomolecular Conformation", E. Platt and B. Robson (1983) "Computers in Biological Science", Eds. M. J. Geisow and A. N. Barrett, (Elsevier Press) pp. 91-131.
67."A Simple Method and BASIC Program for Secondary Structure Prediction on a Microcomputer", B. Robson, G. M. Douglas and J. Garnier, ibid, 132-142.
68."What is a Conservative Substitution?", S. French and B. Robson (1983) J. Mol. Evolution, 19, 171-175.
69."Analysis and Design of Proteins and Peptide Drugs", B. Robson (1984). Proceedings of XIIIth Congress of the International Union of Crystallography.
70."Rational Design of Conformationally flexible drugs", B. Robson and P. W. Finn (1984) ATLA Journal. Alternatives to Laboratory Animals, 11, 67-78.
71. "The Design of Biologically Active Polypeptides", B. Robson (1984) CRC Critical Reviews in Biochemistry. Ed. G Fasman 14, 4, 273-296.
72. "Conformational studies of biomolecules", B. Robson (1984) D.Sc. Thesis
73. "Predictions of the conformation and antigenic determinants of the V-sis viral oncogene product homologous with human platelet derived growth factor", B. Robson, E. Platt, P. W. Finn, P. Millard, J. G. Gibrat and J. Garnier. Int. J. Peptide Protein Res. (1985) 25, pp. 1-8.
74. "Conformational study of Neurotensin", P. W. Finn, B. Robson and E. C. Griffiths. Int. J. Peptide Protein Res. (1985) 24, pp. 407-413.
75. "Conformational calculations on TRH and its analogues", D. J. Ward, E. C. Griffiths, R. G. Robertson and B. Robson. Regul. Peptides. (1985) 13, 73.
76. "Investigation of Conformation-Activity Relationships of Neurotensin Analogues", R. V. Fishleigh, D. J. Ward, E. C. Griffiths and B. Robson (1986) Biological Chemistry (Hoppe-Seyler) 367, 1112-1113.
77. "Introduction to Proteins and Protein Engineering", B. Robson and J. Garnier (1986) 699 pages. Elsevier Press, Amsterdam.
78. "Comparative Conformational Analysis of Leutinizing Hormone Releasing Hormone", R. V. Fishleigh, D. J. Ward, E. C. Griffiths and B. Robson. (1986) Biological Chemistry (Hoppe-Seyler) 367, (Supplement) 266.
79. "Prediction of Preferred Solution Conformers of Analogues and Fragments of Neurotensin", D. J. Ward, R. V. Fishleigh, E Platt, E. C. Griffiths and B. Robson (1986) Regulatory Peptides. 15, 197.
80. "Refined models for computer calculations in protein engineering. Calculation and testing of atomic potential functions compatible with more efficient calculations", B. Robson and E. Platt J. Mol. Biol. (1986) 188, 259-281.
81. "The Prediction of Peptide and Protein Structure", In Practical Protein Chemistry - A Handbook, (Ed. A. Darbre). B. Robson, John Wiley & Sons Ltd, London, 1986, pp. 567-607.
82. "Calculation of the Conformation of Glycosphingolipids 1. D-glucosyl-N-(2-D-hydroxyoctadecanoyl)-D dihydrosphingosine (glucosyl-ceramide) and -D-N-acetylneuraminyl-(2->3)-a-D-galactose", C H Wynn, A. Marsden and B. Robson. J. Theor. Biol. (1986) 119, 81-87.
83. "A conformational study of Met- and Leu-Enkephalins", E C Griffiths, B. Robson and D. J. Ward. Br. J. Pharmacol. (1986) 87, 177S.
84. "Calculation of the conformation of glycosphingolipids: GM1-and GM2-gangliosides", C. H. Wynn, A. Marsden and B. Robson (1986) Biochem. Soc. Trans. 14, 707.
85. "Studies on two novel TRH analogues", C. Baris, E. C. Griffiths, B. Robson, T. Szirtes, D. Starkie and D. J. Ward. Br. J. Pharmacol. (1986) 87, 173S.
86. "A conformational study of thyrotrophin releasing hormone 1. Aspects of importance in the design of novel TRH analogues", D. J. Ward, E. C. Griffiths and B. Robson. Int. J. Peptide Protein Res. (1986) 27, 461-471.
87. "Secondary structure determination as a starting point for tertiary modelisation", J. F. Gilbrat, J. Levin, R. V. Fishleigh, B. Robson and J. Garnier. J. Mol. Graphics (1986) in press.
88. "Approaches to drug design using global energy minimisation, pattern recognition and molecular graphics modelling", B. Robson, D. J. Ward, A. Marsden, R. V. Fishleigh, E. C. Griffiths and E. Platt. J. Mol. Graphics (1986) 4, (4) 235.
89. "Conformational energy calculations on muramyl dipeptide", A. Marsden, B. Robson and J. S. Thompson. Biochem. Soc. Trans. (1986) 14, (3) 530-631.
90. "Conformational energy calculations on the glycan chain of peptidogylcan", A. Marsden, B. Robson and J. S. Thompson. Biochem. Soc. Trans. (1986) 14, (3) 629-630.
91. "A conformational study of neurotensin and some of its analogues", R. V. Fishleigh, D. J. Ward, E. C. Griffiths and B. Robson. Biochem. Soc. Trans. (1986) 14, (6) 1259-1260.
92. "An algorithm for secondary structure determinations in proteins based on sequence similarity", J. Levin, B. Robson and J. Garnier. FEBS Letts. (1986) 205, (2) 303-308.
93. "Computer Aided Peptide and Protein Engineering", in Applied Biotechnology, Proceedings of Biotech 86' Europe, held in London, May 1986. B. Robson, 1, B9-B14.
94. "The EPSITRON concept of peptide and protein engineering. Applications of computer-aided molecular design", B. Robson, D. J. Ward and A. Marsden. (1986) Chemical Design Automated News 1, (7) 9-11.
95. "Computer-Aided peptide and protein engineering", B. Robson. (1986) Applied Biotechnology, 1, B9-B19.
96. "Computer Aided Biomolecular Engineering (Programming Details)", Cyber 205 Newsletter, number 5, January (1986).
97. "Peptide conformation", Royal Society Reports, Royal Society - Sandoz Symposium, 1986. Circulated report
98. "Calculation of the conformation of glycosphingolipids. 2.GM1 and GM2-gangliosides", C. H. Wynn and B. Robson (1986) J. Theor. Biol. 123, 221-230.
99. "Conformational analysis of dynorphins [1-17] and [1-8]", E C Griffiths, B. Robson and D. J. Ward. Br. J. Pharmacol. (1986) 88, 361S.
100. "Artificial Enzymes", B. Robson and A. Marsden (1987) Biochem. Soc. Trans. 15, 119
101. "An expert system for protein engineering. Its application in the study of chloramphenicol acetyltransferase and avian pancreatic polypeptide", B. Robson, E. Platt, R. V. Fishleigh, A. Marsden and P. Millard (1987) J. Mol. Graphics. 5, 8-17.
102. "Computer-aided design and physiological testing of a leuteinising hormone-releasing hormone analogue for 'adjuvant-free' immunocastration", C. A. Morrison, R. V. Fishleigh, D. J. Ward and B. Robson. (1987) FEBS Letts. 214, 65-70.
103. "Studies on rationales for an expert system approach to the analysis of protein sequence data - preliminary analysis of the human epidermal growth factor receptor", R. V. Fishleigh, B. Robson, J. Garnier and P. W. Finn (1987) FEBS Letts. 2, 4, 219-225.
104. "Prediction of HIV Vaccine", B. Robson, R. V. Fishleigh and C. A. Morrison. (1987) Nature, 325, 395
105. "Comparative conformation-activity relationships for Hormonally and centrally acting TRH analogues", D. J. Ward, P. W. Finn, E. C. Griffiths and B. Robson. (1987) Int. J. Peptide Protein Res. 30, 263-274.
106. "Secondary Structure Prediction of TRH Precursors", E. C. Griffiths, P. Millard and B. Robson. (1987) in Thyotrophin-Releasing Hormone, Bethsesda Conference circulated report.
107. "Computer Aided Peptide and Protein Engineering", B. Robson (1987) in "QSAR in Drug Design and Toxicology", Eds.D. Hadzi and B. Jerman-Blazic, Elsevier Press, Amsterdam.
108. "Computer Aided Protein Engineering Software and Hardware Aspects", B. Robson (1987). Applied Biotechnology 2.
109. PATENT: "Analogues of LHRH", R. V. Fishleigh, B. Robson and C. Morrison United Kingdom: Application No. GB 8723072.8. Filed October 1st 1987
110. "Modelling of Alpha-Lactalbumin from the known Structure of Hen-Egg White Lysozyme Using Molecular Dynamics", B. Robson and E. Platt (1987) J. Comp. Aided Molecular Design, 1, 17-22.
111. "Conformational Analysis of Diazepam-Binding Inhibitor Fragments", D. J. Ward, R. V. Fishleigh, E. C. Griffiths and B. Robson, (1987) in "Reports of the 1986 Meeting for Psycho-Pharmacology", A circulated report.
112. "Novel Concepts Behind Novel Methods in Computer-Aided Molecular Design", B. Robson (1988) Transcript of lecture at C.D.C. seminar in Heidelberg.
113. "Introduction to Proteins and Protein Engineering", B. Robson and J. Garnier (1988) 2nd Edition. 699 pages. Elsevier Press. Amsterdam.
114. "Good Vibrations: Dynamics of Proteins and Nucleic Acids", B. Robson, (1988) BioEssays, 8, 93-94.
115. "Investigation of Conformation-Activity Relations of Neurotensin Analogues", (1988) "Molecular Biology of the Nervous System", 367, 112.
116. "Secondary Structure Prediction of the Rat Brain precursor for TRH" E.C.Griffiths, P.Millard and B.Robson, Regulatory Peptides, 22(4) 487
117. "Secondary Structure Prediction: Combination of different methods" V. Biou, J.Garnier and B.Robson (1988), Protein Engineering, 2, 185-192
118. "Further Development of Protein Secondary Structure Prediction Using Information Theory", J. F. Gibrat, J. Garnier and B. Robson. (1988) J. Mol. Biol. 198, 425-443.
119. "Conformational Calculations On Oncogene Products", J. Garnier and B. Robson. (1988) "Computer Simulation of Carcinogenic Processes", Ed. P. D. Silverman, C.R.C Press, Boca Raton, Florida, 67, 90.
120. PATENT: "Synthetic Peptides Related to HIV-env Proteins", R. V. Fishleigh, B. Robson P.C.T. International Patent Application No. PCT/GB88/00491, International Publication No: WO88/10267, dated 29th December 1988
121. "The BioEngine: an Intelligent Supercomputer System for Molecular Analysis, Modelling and Design", B. Robson (1989) published transcripts of "Biotech 1989",
122. "Secondary Structure Prediction of TRH Precursors", E. C. Griffiths, P. Millard and B. Robson. (1989) in Thyotrophin-Releasing Hormone: Biomedical Significance. Eds. G. Metcalf and I. M. D. Jackson, Annals of the New York Academy of Sciences, 553, 487-488.
123. "Secondary Structure Prediction of the Human Rat Precursor of CGRP" E.C.Griffiths, P. Millard, and B. Robson (1989), Regulatory Peptides, 26(1) 73
124. "Secondary Structure Prediction of Neuropeptide Precursor Proteins", E.C. Griffiths, P. Millard, and B. Robson (1989), Biochem. Soc. Trans, 17(2) 419-420.
125. "Computer Aided Peptide and Protein Engineering", B. Robson (1989). in Progress in Clinical and Biological Research, Ed. J. L. Fauchere. Alan R. Liss Inc. New York, 227-231.
126. "Comparative Metabolism and Conformation of TRH and its Analogues", E. C. Griffiths, J. A. Kelly, A. Ashcroft, D. J. Ward and B. Robson. (1989) in Thyrotrophin-Releasing Hormone: Biomedical Significance. Eds. G. Metcalf and I. M. D. Jackson. Annals of the New York Academy of Sciences, 553, 17-237.
127. "The GOR Method for Predicting Secondary Structure in Proteins", J. Garnier and B. Robson (1989) in 'Prediction of Protein Structure and the Principles of Protein Conformation,' Ed. G. D. Fasman, Plenum Publishing Corp. 417-465.
128. "Protean II", B. Robson, P. Millard, and R. V. Fishleigh Commercial GOR Software Release and "Protean II for Schools", Manual, and "COMBINE" GOR (J. Garnier, J.F. Rancois and B. Robson) public domain GOR software for academic use. GOR software in this period was incorporated into some 10 published or otherwise commercially available software (Intelligenetics etc.)
129. "Computer Aided Peptide and Protein-Engineering Software Development", in 'Biotechnology R & D in the EC (BAP) 1985-1989'. (1990) R. Bomford, J. Garnier and B. Robson, (Eds. A Vassarotti and E Magnien). Elsevier, Paris. I, 105.
130. "Computer Aided Peptide and Protein Engineering Software Development", in 'Biotechnology R and D in the EC (BAP) 1985-1989'. (1990) R. Bomford, J. Garnier and B. Robson, (Eds. A Vassarotti and E Magnien). Elsevier, Paris, II, 59-64.
131. "Comparison of the X-ray Structure of Baboon Alpha-Lactalbumin with the Tertiary Predicted Computer Models of Alpha-Lactalbumin", B. Robson and E. Platt, (1990) J. Computer-Aided Molecular Design, 4, 369-379.
132. "A Study of Parallel Molecular Dynamics Algorithms for N-body Simulations on a Transputer System", J. Li, A. Brass, D. J. Ward and B. Robson, (1990), Parallel Computing, 14, 211-222.
133. "A Polymorphic Programming Environment for the Chemical Pharmaceutical and Biotechnology Industries", J. Ball, R. V. Fishleigh, P. J. Greaney, A. Marsden, E. Platt, J. L. Pool and B. Robson. (1990) in 'Chemical Information Systems - Beyond the Structure Diagrams.' Eds. D. Bawden and E. M. Mitchell, Ellis Horwood Press, 107-123.
134. "The Conformation of Peptides During Solid Phase Synthesis", C. Baris, A. Brass, B. Robson and G. Tomalin. (1990). Innovation Perspect Solid Phase Synth Collect Paper. 1st International Symposium SPCC, Birmingham, UK. Ed. R Epton. 89, 441-445.
135. PATENT: "Synthetic Peptides", R. V. Fishleigh, B. Robson. P.C.T. International Patent Application No. PCT/GB91/00392 International Publication No: WO91/13909, dated 19th September 1991
136. "Theoretic Approaches to Drug Design", D. J. Ward, A. M. Brass, J. Li, E. Platt, Y. Chen and B. Robson, (1991) in 'Peptide Pharmaceuticals,' Ed D. J. Ward, Open University Press, 83-129.
137. "The Expert System Approach to Predicting Protein Structure", B. Robson, J. Ball, R. V. Fishleigh, P. J. Greaney, J. Li, A. Marsden, E. Platt and J. L. Pool, (1991) Biochem. Soc. Symp. 57, 91-97.
138. "Influence of the Local Amino Acid Sequence upon the Zones of the Torsional Angles and Adopted by Residues in Proteins", J. F. Gibrat, B. Robson and J. Garnier, (1991). Biochemistry, 30, 1578-1586.
139. "Development and Testing of Protocols for Computer-Aided Design of Peptide Drugs, using Oxtocin", D. J. Ward, Y. Chen, E. Platt and B. Robson, (1991) J. Theor. Biol. 148, 193-227.
140. "A Supermolecule Solvent Model", B. Robson and E. Platt (1991) J. Theor. Biol., Appendix 227-229
141. "Computer Aided Design of Biomolecules: The Big Hammer Approach", B. Robson, E. Platt and J. Li, (1992) in 'Theoretical Biochemistry and Molecular Biophysics' 2 Proteins, Adenine Press, Eds. David L Beveridge and Richard Lavery, 207-222.
142. "Molecular Modelling of the Familial Alzheimer's Disease Mutations in Amyloid Precursor Proteins" F.V. Fishleigh, B.Robson and B. Yanker., Soc. Neuroscience, Abstracts 18 (1-2) 1439
143. "Natural Sequence Code Representations for Compression and Rapid Searching of Human-Genome Style Data Base", B. Robson and P. J. Greaney (1992) CABIOS 8, 283-289.
144. "Exploration of the Phase Space of Molecular Systems: Assessment of Established and New Methods", J. Li, E. Platt, B. Waszkowycz, R. Cotterill and B. Robson (1992) Biophysical Chemistry 43, 221-238.
145. "Case Studies in Automatic Modelling of Thrombin, Alphalactalbumin and other Proteins, and Implications for Drug Design", E. Platt and B. Robson (1992) Proc. R. Soc. Edinburgh 99B, (1/2), 123-136.
146. PATENT: "Fragments of Prion Protein", R. V. Fishleigh, B. Robson and R. P. Mee, .P.C.T. International Patent Application No. PCT/GB92/02246, International Publication No: WO93/11155, dated 10th June 1993
147. "Signal Peptide Research Center" in 'Midterm, Evaluation of the Danish Biotechnological Research and Development Programme (1991-1995)'. Danish Research Councils Committee on Biotechnology. (1993). B. Robson and C.H. Heldin. (Ed. B. S. Larsen) Tekst & Tryk A/S, Vedbaek. 17-18.
148. "The Protein Engineering Research Center" in 'Midterm Evaluation of the Danish Biotechnological Research and Development Programme (1991-1995)'. Danish Research Councils Committee on Biotechnology. (1993). B. Robson and K. Luyben. (Ed. B. S. Larsen) Tekst & Tryk A/S, Vedbaek. 19-21.
149. "Center for Human Genome Research" in 'Midterm Evaluation of the Danish Biotechnological Research and Development Programme (1991-1995)'. Danish Research Councils Committee on Biotechnology. (1993). R. Dedonder, U. Hacksell and B. Robson. (Ed. B S Larsen) Tekst & Tryk A/S, Vedbaek. 22-23.
150. "Hybrid Monte Carlo Simulations Theory and Initial Comparison with Molecular Dynamics", B. Robson, A. Brass, Y. Chen and B. J. Pendleton. (1993) John Wiley & Sons. Biopolymers 33, 1307-1315.
151. "Protein Structure Prediction", B. Robson and J. Garnier (1993) Nature 361, 506.
152. PATENT: "Synthetic Polypeptides", R. V. Fishleigh, B. Robson and R. Aston, B.P.C.T. International Patent Application No. PCT/GB93/00808 International Publication No: WO93/21218, dated 28th October 1993
153. "A Method for Rapidly Assessing and Refining Simple Solvent Treatments in Molecular Modelling. Example Studies on the Antigen-Combining Loop H2 from FAB Fragment McPC603", V. P. Collura, P. J. Greaney and B. Robson (1994) Protein Engineering. 7, 221-233,
154. 'Analogues of Piscine LHRH' R. V. Fishleigh, B. Robson, P.C.T. International Patent Application No. PCT/GB92/0004International Publication No: WO92/12247, dated 23rd July 1994
155. "Novel Algorithms for Searching Conformational Space", D. Byrne, J. Li, E. Platt, B. Robson and P. Weiner. (1994) J.Comp.Aided.Mol.Des. 8, 67-82.
156. "PRO_LIGAND: An Approach to De Novo Molecular Design. 1. Application to the Design of Organic Molecules", D. E. Clark, D. Frenkel, S. A. Levy, C. W. Murray, B Robson, B. Waszkowycz and D. R. Westhead. (1995) J.Comp.Aided.Mol.Des. 9, 13-32
157. "PRO_LIGAND: An Approach to De Novo Design. 2. Design of Novel Molecules from Molecular Field Analysis (MFA) Models and Pharmacophores", B. Waszkowycz, D. E. Clark, D. Frenkel, J. Li, C. W. Murray, B. Robson and D. R. Westhead. (1994) J.Med.Chem., 37, 3994-4002
158. "PRO_LIGAND: An Approach to De Novo Molecular Design. 3. A Genetic Algorithm for Structure Refinement", D. R. Westhead, D. E. Clark, D. Frenkel, J. Li, C. W. Murray, B. Robson and B. Waszkowycz. (1995) J.Comp.Aided.Mol.Des. 9, 139-148
159. "PRO_LIGAND: An Approach to De Novo Molecular Design. 4. Application to the Design of Peptides", D. Frenkel, D. E. Clark, J. Li, C. W. Murray, B. Robson, B. Waszkowycz and D. R. Westhead. (1995). J. Comp. Aided Mol. Des. 9, 213-225
160. "Ligand: A New Automated System for De Novo Drug Design", C. W. Murray, D. E. Clark, A. D. Frenkel, J. Li, B. Robson, B. Waszkowycz and D. R. Westhead. (1994) Proceedings of the 1st European Conference on Computational Chemistry, circulated proceedings.
161. PATENT: "Peptides Related to Mycobacterium Bovis Proteins", 'R. V. Fishleigh, B. Robson and P. J. Greaney, P.C.T. International Patent Application No. PCT/GB93/01527 International Publication No: WO94/02508, dated 3rd February 1994
162. PATENT: "IPNV Vaccine", R. V. Fishleigh, B. Robson and P. J. Greaney, P.C.T. International Patent Application No. PCT/GB93/01812, International Publication No: WO94/04565, dated 3rd March 1994
163. "Automatic Drug Design Methods", B. Robson, J. Li, D. E. Clark, D. Frenkel, C.W. Murray, D. R. Westhead and B. Waszkowycz. Perspectives on Protein Engineering Symposium, Oxford 1994, Circulated proceedings 1995.
164. "Mitchell - A Man for All Seasons", B. Robson (1994) Obituary and appraisal of his thoughts on the possibility automated drug design, The Biochemist, Oct/Nov 1994, pp. 46.
165. "Parallel Processing, Expert Systems and Designer compounds", B. Robson (1995) in "Parallel Processing in Commercial and Industrial Applications", Unicom Seminars Ltd., Ed. Francis Wray.
166. "Reduced Variable Molecular Dynamics", J. Turner, P. K. Weiner, B. Robson, R. Venugopal, W. H. Schubele III, and R. Singh. (1995). Journal of Computational Chemistry, 16, 1271-1290
167. "GOR Method for Predicting Protein Secondary Structure from Amino Acid Sequence", J. Garnier, J. Francoise and B. Robson (1996) in Methods in Enzymology, 266 ("Computer Methods for Macromolecular Sequence Analysis", Ed. R.F. Dolittle).
168. Contributed Section to Report on NIH Symposium Protein Folding and Design (1996) - Chemical Engineering News, May 27, p32-33, (Subject Matter Reproduced in NHI Circulated Report & CHI Symposia on "Development of Small molecule Mimetics,", 1996, Circulated report)
169. "Doppelganger Proteins as Drug Leads", B. Robson (1996), Nature Biotechnology, 14, 892-893
170. "N-Alkoxy amid backbone protection in BOC chemistry : improved synthesis of a 'difficult sequence'", L. E. Canne, G. M. Figliozzi, B. Robson, M. A. Siani and R. J. Simon (1996), Protein Science, 5, Suppl.1, 72 [published poster 82-M]
171. "Chemical synthesis and activity of D-superoxide dismutase", G. M. Figliozzi, M. A. Siani, L. E. Canne, B. Robson, and R. J. Simon (1996) Protein Science, 5, Suppl.1, 72, [published poster 87-S]. See also "Total Chemical Synthesis of Proteins including Chemokines and their Analogues", M. A. Siani, L. E. Canne, G. M. Figliozzi, B. Robson, D. A. Thompson and R. J. Simon , circulated in "Chemokines", International Business Communications (1997)
172. Danish Research Council Update Report: "Evaluation of the Danish Biotechnological Research and Development Programme" - "Signal Peptide Research Center", B. Robson , Danish Research Councils Committee on Biotechnology, "The Protein Engineering Research Center", B. Robson , "Center for Human Genome Research", B. Robson (Ed. B S Larsen) (1995)
173. "Reduced Variable Molecular Dynamics", J. Turner, P.K. Weiner, B. Robson, R. Venugopal, H. Schubele II and R. Singh (1997), pp 122-149 in "Computer Simulation of Biomolecular Systems. Theoretical and Experimental Applications.", Vol III, Eds. W. F. van Gunsteren, P. K. Weiner and A. J. Wilkinson, pub.Kluwer-ESCOM .
174. "Computer Languages in Pharmacology", B. Robson (1997), pp 494-562 in "Computer Simulation of Biomolecular Systems. Theoretical and Experimental Applications.", Vol III, Eds. W. F. van Gunsteren, P. K. Weiner and A. J. Wilkinson, pub.Kluwer-ESCOM.
175. "Fast Track Routes from Genome to Peptidomimetic" B.Robson (1998) in "Peptidomimetics & Small Molecule Design", Eds. W. Hori, E.M.Nagle, and L.M.Savage,
176. "High Throughput Insight: Web-based collections of bioinformatics tools catalyses scientific inquiry into subtle aspects of gene structure and Function" Dennis Smith and Barry Robson, IBC Library Series
177. J. Li and B. Robson (2000), “Bioinformatics and Computational Chemistry in molecular Design. Recent Advances and their Application” pp 285-307 in Peptide and Protein Drug Analysis Marcel Dekker NY
178. “Beyond Proteins” B. Robson (1999) Trends Biotechnology,17:311-315
179. “Simplified Models of Protein Folding Exploiting the Lagrange Radius of Gyration of the Hydrophobic Component” B. Robson (2000) Parallel Computing 26,977-998
180. “Fastfinger: A study into the use of compressed residue pair separation matrices for protein
sequence comparison” B. Robson (2001), IBM Systems Journal 40. Also available on http://www.research.ibm.com/journal/sj/402/robson.html
181. “Studies in the Assessment of Folding Quality for Protein Modeling and Simulation when the Experimental Structure is Unknown”. (J. Proteomics Res. (Am. Chem. Soc)., B.Robson (2002), Vol 1, No. 2, 115-133
182. “The future of highly personalized health care". B.Robson (2002) Stud Health Technol Inform. 80:163-74.