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Barry Robson BSc(Hons) PhD DSc (IBM
Distinguished Engineer), is Strategic Advisor at IBM’s T. J. Watson
Research Center, at Yorktown Heights, NY, where he played a key role in
proposals leading to IBM's DiscoveryLink, Blue Gene protein science and
Secure Health and Medical Access Network (S.H.A.M.A.N.) projects. He is
active within and outside IBM in regard to studies in innovation and technical
vitality at corporate and national level; he served on the Innovation
Frontiers and the National Innovation Initiative and contributed to the
important report “Innovate America. National Innovation Initiative
Report” (Council on Competitiveness, December 2004). He is also
Program Director Computational Medicine, Council Member of the Deep Computing
Institute, an Organizer of the IBM Academy of Technology Study on Enabling
Technologies for Information Based Medicine, and a consultant and advisor
within IBM’s “On Demand Services” program. He was recently
Professional Interest Communities Chair in computational biology and medicine
and will continue to participate through the contemporary Chair. His scientific
and medical expertise and interests at IBM are in regard to biomolecular
medicine, healthcare and the digital patient record with pharmacogenomic
and other data, information technology support of bio-ethics, and high
dimensional clinical data mining for diagnosis, prognosis, and research.
In addition to his IBM roles, Barry is also Honorary Professor of Clinical
Informatics and Molecular Sciences at St Matthews Medical School, Grand
Cayman, and Chair of The Dirac Foundation at the Department of Experimental
Surgery and Oncology at St. Mary's Hospital, Imperial College London.
The foundation was formed by Barry with the support of Margit Dirac widow
of Nobel Laureate Paul Dirac to honor Professor Dirac and to promote understanding
of the importance of theoretical physics, chemistry, and biology to human
and veterinary medicine. Recently (2001-2004), he also held the title
of Professorial Lecturer at Mount Sinai Medical School, New York.
Barry was trained as a medical scientist and later in computational chemical
physics. According to an article in Nature (389,418-420,1997), he was
a pioneer in bioinformatics, protein modeling, and computer-aided drug
design. He was awarded the Asklepios Statue Future of Health Technology
Award at the Future of Health Technology Summit 2001 at MIT, for “outstanding
breakthrough innovators and leaders who made significant impact on the
future of health technology.” He has sat on the board of five biopharmaceutical
companies and scientific founder or cofounder of several commercial and
semi-commercial R&D organizations. This includes the Proteus group
of pharmaceutical companies where as founder he served as Science Director
for some 9 years, helping take Proteus International plc successfully
to the London Stock exchange in 1990 (now Protherics plc). During that
period or earlier Barry was consultant to several major pharmaceutical
companies and was advisor to, or served for, to the Danish Research Council,
the European Commission, the Bioindustry Association, and the European
Bioinformatics Institute and various publishing bodies. At the end of
the "Cold War" Barry also assisted Feinstein Partners (Cambridge
Mass.) working with a government official exploring possibilities for
US-Russian scientific collaboration via the Internet. Barry has variously
held Readerships or Professorships or similar at the Universities of Manchester
and South Paris, and the Technical High School of Denmark, and as Common
Room Fellow of Wolfson College Oxford. Later he was Visiting Scholar lecturing
in bioinformatics at Stanford University Medical School in California
where he also assisted companies in the industrialization phase of start-up
ventures, including Gryphon Sciences as CSO and MDL Information Systems
as Principal Scientist.
As a researcher Barry is author of some 200 papers, books and patents.
He developed the Bayesian and information-theoretic basis for bioinformatics
in a series of papers in Nature and the Journal of Molecular Biology from
1970-1978; the 1970 Nature paper with Roger Pain is believed to be the
first to do protein structure prediction on a statistical quantitative
basis, and the 1978 paper with Jean Garnier and David Osguthorpe was designated
a multiple "Citation Classic" by the Institute for Scientific
Information and in 1999 this paper was described on the Journal of Molecular
Biology web page as the number 11 in the top 100 most cited J.Mol.Biol.
papers for 40 years. More recently, his paper on the Genomic Messaging
System with Richard Mushlin was judged a paper of special merit and made
a press release by the American Chemical Society, and was cited as one
of nine top technologies to watch by Healthcare Informatics magazine.
He is coauthor of the widely used 700 page university textbook "Introduction
to Proteins and Protein Engineering" by Robson and Garnier. Barry
was also a Nature "New and Views" correspondent on proteins
and related matters for some five years. Barry was coinventor of various
clinical and veterinary products, including the Protherics/Enfer diagnostic
for Mad Cow Disease marketed by Abbott, early HIV diagnostics in work
which included the earliest publication in Nature of proposed HIV epitopes
for vaccine work, methods of biosensors and synthetic chemistry, clinical
systems and data mining, and of various commercial molecular analysis
and design systems and languages in industrial use. Barry is also with
Jean Garnier (Chair of the IUPAB and IUBG) the coordinator of the Bioinformatics
Industrialization Workshops on medicine hosted at the Whitehead Institute,
Cambridge Mass. and the European Bioinformatics Institute, Hinxton UK.
The ongoing Workshops are variously sponsored by the US Department of
Energy, The Deep Computing Institute, IBM Life Sciences, The Wellcome
Trust, and the International Union of Pure And Applied Biophysics, which
at Hinxton with the InterUnions Bioinformatics Group, with Barry as Taskforce
advisor, submitted the recent "Whitepaper" report on the state
and quality of bioinformatics to UNESCO and the ICSU.
Barry is a member of The Biochemical Society (UK), biomedical-related
standards bodies including HL7 Inc. He is also a principal investigator
or similarly active in several scientific collaborations, concerning clinical
data and healthcare or education, including Cambridge University UK, The
University of British Columbia, a Virginia state-wide university-based
digital record initiative, the University of California San Francisco,
Boston University.
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