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IBM Watson Research Center

Alice Carolyn McHardy, PhD

 

I joined the Bioinformatics and Pattern Discovery Group at the T.J. Watson Research Center in January, 2005 as a postdoctoral researcher. For a list of my research interests and related things, see below.

 

Research interests

 

  • Analysis of metagenomic data
  • Comparative genomics
  • Prokaryotic gene identication
  • Horizontal gene transfer (HGT)
  • Genome annotation and Annotation Systems

 

 

Curriculum vitae

 

  • 03/04: PhD, Computer Science, Technical Department, Bielefeld University, Germany
  • 11/00: Diploma (MS), Biochemistry, Department of Chemistry, Bielefeld University, Germany

 

 

 

Publications

 

  • Thieme, F., Koebnik, R., Bekel, T., Berger, C., Boch, J., Büttner, D., Caldana, C, Gaigalat, L., Goesmann, A., Kay, S., Kirchner, O., Lanz, C., Linke, B., McHardy, A.C., Meyer, F., Mittenhuber, G., Nies, D. H., Niesbach-Klösgen, U., Patschkowski, T., Rückert, C., Rupp, O., Schneiker, S., Schuster, S.C., Vorhölter, F., Weber, E., Pühler, A., Bonas, U., Bartels, D. and Kaiser, O. (2005), Novel insights into genome plasticity and pathogenicity of the plant pathogenic bacterium Xanthomonas campestris pv. vesicatoria revealed by the complete genome sequence, J. Bac., in press

 

  • A.C. McHardy, A. Goesmann, A. Puehler, F. Meyer (2004). Development of joint application strategies for two microbial gene finders, Bioinformatics, 20:1622-31

 

·        A.C. McHardy, J. Kalinowski, A. Puehler, F. Meyer (2004). Comparing expression level-dependent features in codon usage with protein abundance: An analysis of predictive proteomics, Proteomics 4: 46-58

 

·        Wilke, C. Rueckert, D. Bartels, M. Dondrup, A. Goesmann, A. Hueser, S. Kespohl, B. Linke, M. Mahne, A.C. McHardy, A. Puehler, F. Meyer (2003). Bioinformatics support for high-throughput proteomics, J. Biotechnol. 106: 147-56

 

·        Goesmann, B. Linke, O. Rupp, L. Krause, D. Bartels, M. Dondrup, A.C. McHardy, A. Wilke, A. Puehler, F. Meyer (2003). Building a BRIDGE for the integration of heterogeneous data from functional genomics into a platform for systems biology, J. Biotechnol. 106: 157-67

 

·        J. Kalinowski, B. Bathe, D. Bartels, N. Bischoff, M. Bott, A. Burkovski, N. Dusch, L. Eggeling, B.J. Eikmanns, L. Gaigalat, A. Goesmann, M. Hartmann, K. Huthmacher, R. Kraemer, B. Linke, A.C. McHardy, F. Meyer, B. Mockel, W. Pfefferle, A. Puehler, D.A. Rey, C. Rueckert, O. Rupp, H. Sahm, V.F. Wendisch, I. Wiegraebe, A. Tauch (2003). The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins, J. Biotechnol. 104: 5-25

 

·        A.C. McHardy, A. Tauch, C. Rueckert, A. Puehler, J. Kalinowski (2003). Genome-based analysis of biosynthetic aminotransferase genes of Corynebacterium glutamicum, J. Biotechnol. 104: 229-40

 

  • F. Meyer, A. Goesmann, A.C. McHardy, D. Bartels, T. Bekel, J. Clausen, J. Kalinowski, B. Linke, O. Rupp, R. Giegerich, A. Puehler (2003). GenDB--an open source genome annotation system for prokaryote genomes, Nucleic Acids Res. 31: 2187-95

 

 

Awards

 

  • ISMB Best Poster Award, 2002: Alice McHardy, Jan Kleinluetzum and Folker Meyer, Expert-system based annotation strategies using GenDB, an open source genome annotation system.

 


Alice Carolyn McHardy, PhD
Bioinformatics & Pattern Discovery Group
Computational
Biology Center 
IBM Thomas J. Watson Research Center

PO Box 218
Yorktown Heights, NY 10598, U.S.A.
 

Phone: +1-914-945-1394
Fax:     +1-914-945-4104


Email: acmchard@us.ibm.com 

  

 

 

 

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