Cellular assays are used to study how chemicals, biomolecules and factors such as electrical and mechanical stimuli, radiations, and heat affect the viability, metabolism, differentiation, cytoskeleton, motility, adhesion, receptor trafficking, and apoptosis processes of cells. Cellular assays therefore are of fundamental importance in biology, medicine, pharmacology and biotechnology. They are used both at a fundamental research level as well as for diagnostics.
We have developed a method for depositing cell populations in a microfluidic device, stimulating the cells, and creating a biomolecular cascade between the cells. This technology provides scientists a powerful yet flexible method for performing research in life sciences and helps them tackle the origin of several diseases such as those affecting the human brain.
We are undertaking this effort in collaboration with Prof. Matteoli (University of Milano) and Dr. Bianco (Neuro-Zone srl, Milano), who are veterans in the field of neuroscience.