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Advances in information technology systems and applications are rapidly changing medical research and clinical practice in a variety of ways, including accelerating the process of drug discovery and testing, facilitating the collection of statistics for research, and facilitating personalized treatment based on a patient's history and genetic data. This issue contains 12 papers describing health-care technology interoperability and standards, advances in imaging and telemedicine, clinical decision-support systems, and other emerging technologies.
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Introduction
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Catherine Lasser, Vice President, IBM Industry Solutions and Emerging Business and Michael Svinte, Vice President, IBM Global Innovation and Information-Based Medicine
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Preface
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Joseph M. Jasinski, Program Director, Healthcare and Life Sciences, IBM Research, David I. Seidman, and John J. Ritsko
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p. 3
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Interoperability and standards
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A health-care data model based on the HL7 Reference Information Model
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T. J. Eggebraaten, J. W. Tenner, and J. C. Dubbels
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p. 5
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Varieties of interoperability in the transformation of the health-care information infrastructure
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B. A. Eckman, C. A. Bennett, J. H. Kaufman, and J. W. Tenner
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p. 19
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The Health Record Banking imperative: A conceptual model
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J. D. Gold and M. J. Ball
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p. 43
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The seventh layer of the clinical-genomics information infrastructure
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A. Shabo and D. Dotan
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p. 57
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Imaging and telemedicine
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The innovative bundling of teleradiology, telepathology, and teleoncology services
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R. S. Weinstein, A. M. López, G. P. Barker, E. A. Krupinski, M. R. Descour, K. M. Scott, L. C. Richter, S. J. Beinar, M. J. Holcomb, P. H. Bartels, R. A. McNeely, and A. K. Bhattacharyya
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p. 69
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Monitoring chronically ill patients using mobile technologies
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C. Kirsch, M. Mattingley-Scott, C. Muszynski, F. Schaefer, and C. Weiss
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p. 85
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Remote health-care monitoring using Personal Care Connect
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M. Blount, V. M. Batra, A. N. Capella, M. R. Ebling, W. F. Jerome, S. M. Martin, M. Nidd, M. R. Niemi, and S. P. Wright
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p. 95
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Clinical decision intelligence: Medical informatics and bioinformatics
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MedTAKMI-CDI: Interactive knowledge discovery for clinical decision intelligence
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A. Inokuchi, K. Takeda, N. Inaoka, and F. Wakao
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p. 115
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A graph-theoretical approach for pattern discovery in epidemiological research
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R. A. Mushlin, A. Kershenbaum, S. T. Gallagher, and T. R. Rebbeck
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p. 135
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Infrastructure for a clinical-decision-intelligence system
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X. S. Wang, L. Nayda, and R. Dettinger
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p. 151
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Biobanking and biomarkers
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BIMS: An information management system for biobanking in the 21st century
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G. Ölund, P. Lindqvist, and J.-E. Litton
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p. 171
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IT solutions for imaging biomarkers in biopharmaceutical research and development
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M. Hehenberger, A. Chatterjee, U. Reddy, J. Hernandez, and J. Sprengel
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p. 183
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